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New F.W. Olin Physical Sciences Building
 
Chemistry Department
150 W University Blvd
Melbourne, FL 32901

Dr. Mike Babich,
Department Head
103 Olin Physical Sciences
Phone: (321) 674 - 8046
Fax: (321) 674 - 8951
babich@fit.edu

Selected Publications by Joshua Rokach

The First Total Synthesis of iPF-VI and Its Deuterated Analog.  Kim, S.; Lawson, J. A.; Pratico, D.; FitzGerald, G. A.; Rokach, J.  Tetrahedron Lett., 43, 2801-2805 (2002).

Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometric Analysis of the Four Classes of F2-Isoprostanes in Human Urine.  Li, H.; Lawson, J. A.; Reilly, M.; Adiyaman, M.; Hwang, S. W.; Rokach, J.; FitzGerald, G. A.  Proc. Natl. Acad. Sci. USA, 96, 13381-13386 (1999).

Isoprostanes: Formation, Analysis and Use as Indices of Lipid Peroxidation In VivoJ. Biol. Chem., 274, 24441-24444 (1999).

Vitamin E Suppresses Isoprostane Generation In Vivo and Reduces Atherosclerosis in ApoE-Deficient Mice.  Pratico, D.; Tangirala, R. K.; Rader, D. J.; Rokach, J.; FitzGerald, G. A.  Nature Med., 4, 1189-1192 (1998).

Diels-Alder Approach to Isoprostanes.  Total Synthesis of iPF-V.  Pudukulathan, Z.; Manna, S.; Hwang, S. W.; Khanapure, S. P.; Lawson, J. A.; FitzGerald, G. A.; Rokach, J.  J. Am. Chem. Soc., 120, 11953-11961 (1998).

First Total Synthesis of Isoprostane IPF-III.  Adiyaman, M.; Li, H.; Lawson, J. A.; Hwang, S. W.; Khanapure, S. P.; FitzGerald, G. A.; Rokach, J.  Tetrahedron Lett., 38, 3339-3342 (1997).

Synthesis of 10,11-Dihydro-12-oxo-LTB4, a Key Biochemical Intermediate.  Khanapure, S. P.; Wang, S. S.; Powell, S. W.; Rokach, J.  J. Org. Chem., 62, 325-330 (1997).

Total Synthesis of 2-Epi-PGF.  Hwang, S. W.; Adiyaman, M.; Khanapure S. P.; Rokach, J.  Tetrahedron Lett., 37, 779-782 (1996).

Deblocking of Dithioacetals and Oxathioacetals Using Periodic Acid Under Mild Nonaqueous Conditions.  Shi, X.-X.; Khanapure, S. P.; Rokach, J.  Tetrahedron Lett., 37, 4331-4334 (1996).

Total Synthesis of a Novel Isoprostane IPF-I and Its Identification in Biological Fluids.  Adiyaman, M.; Lawson, J. A.; Hwang, S. W.; Khanapure, S. P.; FitzGerald, G. A.; Rokach, J.  Tetrahedron Lett., 37, 4849-4852 (1996).

Total Synthesis of 8-Epi-PGF.  A Novel Strategy for the Synthesis of Isoprostanes.  Hwang, S. W.; Adiyaman, M.; Khanapure, S.; Schio, L.; Rokach, J.  J. Am. Chem. Soc., 116, 10829-10830 (1994).

 

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