Shengyuan Yang

Associate Professor | Mechanical and Civil Engineering

Contact Information

syang@fit.edu
(321) 674-8804
F.W. Olin Engineering Complex, 217

Educational Background

Ph.D. University of Illinois at Urbana-Champaign 2007
B.Eng. University of Science and Technology of China 1993

Professional Experience

Associate Professor, Department of Mechanical and Civil Engineering, Florida Institute of Technology, March 2018-present

Assistant Professor, Department of Mechanical and Aerospace Engineering, Florida Institute of Technology, August 2007-February 2018

Current Courses

Undergraduate Courses:

MEE 2024: Solids Modeling

MEE 2081: Applied Mechanics: Statics

MEE 2081: Applied Mechanics: Dynamics

MEE 3083: Mechanics of Materials

MEE 3090: Design of Machine Elements

MEE 3091: Theory of Machines

Graduate Courses:

MEE 5410: Elasticity

MEE 5460: Fracture Mechanics

Selected Publications

Shengyuan Yang, “Curvature-defined culturing technology – A new tool for the studies of stem cell mechanobiology: A perspective,” Stem Cell Research & Therapeutics, Vol. 5, No. 1, 2020, 146-163 (an invited review and perspective paper).

Sang Joo Lee and Shengyuan Yang, “Substrate curvature restricts spreading and induces differentiation of human mesenchymal stem cells,” Biotechnology Journal, Vol. 12, No. 9, 2017, Art. No. 1700360.

Sang Joo Lee and Shengyuan Yang, Micro glass ball embedded gels to study cell mechanobiological responses to substrate curvatures, Review of Scientific Instruments, Vol. 83, No. 9, 2012, Art. No. 094302.

Scott Siechen, Shengyuan Yang, Akira Chiba, and Taher Saif, Mechanical tension contributes to clustering of neurotransmitter vesicles at presynaptic terminals, Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 106, No. 31, 2009, pp. 12611-12616.

Shengyuan Yang and Taher Saif, Microfabricated force sensors and their applications in the study of cell mechanical response, Experimental Mechanics, Vol. 49, No. 1, 2009, pp. 135-151 (invited).

(Book) Shengyuan Yang, Micromachined Sensors to Study Cell Mechanical Response, VDM Verlag Dr. Mller, Saarbrcken, Germany, 2008.

Shengyuan Yang, Scott Siechen, Jie Sun, Akira Chiba, and Taher Saif, MEMS based sensors to explore the role of tension in axons for neuro-transmission, Technical Digest of the 21th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2008), January 13-17, 2008, Tucson, Arizona, USA, pp. 308-310.

Shengyuan Yang and Taher Saif, MEMS based force sensors for the study of indentation response of single living cells, Sensors and Actuators A, Vol. 135, No. 1, 2007, pp. 16-22.

Shengyuan Yang and Taher Saif, Force response and actin remodeling (agglomeration) in fibroblasts due to lateral indentation, Acta Biomaterialia, Vol. 3, No. 1, 2007, pp. 77-87.

Shengyuan Yang and Taher Saif, Mechanical behavior of single living fibroblasts by micro force sensors, Proceedings of the Third International Conference on Multiscale Materials Modeling (MMM 2006), September 18-22, 2006, Freiburg, Germany, pp. 654-656.

Shengyuan Yang and Taher Saif, Microinstruments for single cellular studies, Technical Digest of the Ninth International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS 2005), October 9-13, 2005, Boston, Massachusetts, USA, pp. 900-902.

Shengyuan Yang and Taher Saif, Reversible and repeatable linear local cell force response under large stretches, Experimental Cell Research, Vol. 305, No. 1, 2005, pp. 42-50.

Shengyuan Yang and Taher Saif, Micromachined force sensors for the study of cell mechanics, Review of Scientific Instruments, Vol. 76, No. 4, 2005, Art. No. 044301. (Listed in Virtual Journal of Biological Physics Research, Vol. 9, No. 7, 2005.)

Shengyuan Yang and Taher Saif, Mechanical response of single living cells by bio-MEMS sensors, Technical Digest of the 17th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2004), January 25-29, 2004, Maastricht, The Netherlands, pp. 265-267.

Recognition & Awards

NSF CAREER Award, 2009

Research

Development of MEMS/NEMS force sensors, platforms, and substrates to study mechanobiological responses of living cells

Research & Project Interests

Micro and nano electro mechanical systems (MEMS/NEMS), cell and tissue mechanics and mechanobiology, bio-MEMS/NEMS, and mechanics of materials.

Patents

  1. Shengyuan Yang, “Methods and kits for cell sorting,” United States Patent No.: US 10,871,435, Date of Patent: December 22, 2020.

  2. Shengyuan Yang, “Methods and kits for directing cell attachment and spreading,” United States Patent No.: US 10,738,276, Date of Patent: August 11, 2020.

  3. Shengyuan Yang, “Micro and nano scale structures disposed in a material so as to present micrometer and nanometer scale curvature and stiffness patterns for use in cell and tissue culturing and in other surface and interface applications,” United States Patent No.: US 9,512,397, Date of Patent: December 6, 2016.

  4. Shengyuan Yang, “Versatile, flexible, and robust MEMS/NEMS sensor for decoupled measuring of three-dimensional forces in air or liquids,” United States Patent No.: US 9,021,897, Date of Patent: May 5, 2015.

  5. Shengyuan Yang, “Micro and nano glass balls embedded in a gel presenting micrometer and nanometer scale curvature and stiffness patterns for use in cell and tissue culturing and a method for making same,” United States Patent No.: US 8,802,430, Date of Patent: August 12, 2014.

  6. Shengyuan Yang, “Substrates with micrometer and nanometer scale stiffness patterns and curvature patterns,” China Utility Mode Patent No.: ZL 2013 2 0124977.5, Date of Patent: December 11, 2013.

  7. Shengyuan Yang, “Methods and kits for guided stem cell differentiation,” United States Patent Pending, Application No.: 15652938, Date of Application: July 18, 2017.

  8. Shengyuan Yang, “Curvature-defined concave and convex PDMS surfaces for use in cell and tissue culturing and in other surface and interface applications,” United States Patent Pending, Application No.: 16713644, Date of Application: Dec. 13, 2019.

  9. Shengyuan Yang, “Curvature-defined convex and concave gel surfaces for use in cell and tissue culturing and in other surface and interface applications,” United States Patent Pending, Application No.: 16713756, Date of Application: Dec. 13, 2019.

  10. Shengyuan Yang, “Methods of using curvature-defined surfaces with varying curvatures to direct cell attachment, spreading, and migration,” United States Patent Pending, Application No.: 16713889, Date of Application: Dec. 13, 2019.