Research at Florida Tech > Protocol Prep Flowchart

Protocol Prep Flowchart

I am planning research that involves vertebrate animals.

Is this a work collaboration?
- YES
  - Complete Inter-institutional Agreement for Animal Responsibilities (for collaborations)
- NO
  - Go to Step 2
Begin Protocol Preparation
Personnel working on research are trained and part of the occupational health program?
- YES
  - Go to Step 4
- NO
  - Complete CITI courses
  - Enroll in Animal Contact Program
Related approvals acquired or in review?
- YES
  - Go to Step 5
- NO
  - Biological & Chemical Materials, Pharmaceuticals & Controlled Substances, Radioactive Materials
Protocol includes ALL of the following details:
- Rationale & purpose of animal use
- Clear description of animal procedures
- Consideration of alternatives, the 3 Rs
- Justification of animal numbers
- Unnecessary duplication of experiments
- Housing & husbandry
- Impact of procedures on animal well-being
- Appropriate sedation, analgesia, anesthesia
- Conduct of surgical procedures
- Postprocedural care and observation
- Description & rationale for endpoints
- Criteria for removal of animals from study
- Disposition of animals, euthanasia methods
- Training & experience, personnel roles
- Hazards, safe environment
- YES
  - Go to Step 6
- NO
  - Standard Operating Procedures
  - Additional Resources
Submit for pre-review
- Returned for completion
  - Complete and re-submit for pre-review
- Sent to IACUC for review
  - Proceed to Step 7
Designated Member Review (DMR) if Full Committee Review is not requested
- PI notified of required modifications
  - Repeat step 7
- Approval issues to PI, PI maintains protocol.
  - Submit Changes to Protocol (species, personnel, procedures, etc.) to IACUC for review
  - Submit Annual Renewal Report before 1st and 2nd anniversaries to IACUC for review
  - Submit New Protocol before 3rd anniversary to IACUC for review