Research at Florida Tech

Protocol Prep Flowchart

I am planning research that involves vertebrate animals.

1. Is this a work collaboration?
   • YES
     • Complete Inter-institutional Agreement for Animal Responsibilities (for collaborations)
   • NO
     • Go to Step 2
2. Begin Protocol Preparation
3. Personnel working on research are trained and part of the occupational health program?
   • YES
     • Go to Step 4
   • NO
     • Complete CITI courses
     • Enroll in Animal Contact Program
4. Related approvals acquired or in review?
   • YES
     • Go to Step 5
   • NO
     • Biological & Chemical Materials, Pharmaceuticals & Controlled Substances, Radioactive Materials
       
       
5. Protocol includes ALL of the following details:
   • Rationale & purpose of animal use
   • Clear description of animal procedures
   • Consideration of alternatives, the 3 Rs
   • Justification of animal numbers
   • Unnecessary duplication of experiments
   • Housing & husbandry
   • Impact of procedures on animal well-being
   • Appropriate sedation, analgesia, anesthesia
   • Conduct of surgical procedures
   • Postprocedural care and observation
   • Description & rationale for endpoints
   • Criteria for removal of animals from study
   • Disposition of animals, euthanasia methods
   • Training & experience, personnel roles
   • Hazards, safe environment
     
     
   • YES
     • Go to Step 6
   • NO
     • Standard Operating Procedures
     • Additional Resources
       
       
6. Submit for pre-review
   • Returned for completion
     • Complete and re-submit for pre-review
   • Sent to IACUC for review
     • Proceed to Step 7
7. Designated Member Review (DMR) if Full Committee Review is not requested
   • PI notified of required modifications
     • Repeat step 7
       
       
   • Approval issues to PI, PI maintains protocol.
     • Submit Changes to Protocol (species, personnel, procedures, etc.) to IACUC for review
     • Submit Annual Renewal Report before 1st and 2nd anniversaries to IACUC for review
     • Submit New Protocol before 3rd anniversary to IACUC for review